1. Antagonists of serotonin receptor subtype 5-HT6. VI. The synthesis and structure-activity relationship of substituted 3-(phenylsulfonyl)quinoline. Ivachtchenko A.V., Golovina E.S., Kadieva M.G. et al., Khim.-Farm. Zh. (Russian) 2014, 48, (10), 14-28.
2. Add-on clinical effects of selective antagonist of 5-HT6 receptors AVN211 (CD0080173) in patients with schizophrenia stabilized on antipsychotic treatment: pilot study. Morozova M.A., Lepilkina T.A., Rupchev G.E. et al., CNS Spectrums / FirstView Article / 2013, 1-8.
3. Synthesis of Substituted Diphenyl Sulfones and Their Structure-Activity Relationship with the Antagonism of 5-??6 Receptors. Ivachtchenko A.V., Golovina E.S., Kadieva M.G. et al. Bioorg. Med. Chem. Lett. 2013, 21, 4614-4627.
4. Antagonists of 5-HT6 receptors. Substituted 3-(phenylsulfonyl)-pyrazolo[1,5-a]pyrido[3,4-e]pyrimidines and 3-(phenylsulfonyl)-pyrazolo[1,5-a]pyrido[4,3-d]pyrimidines — synthesis and «structure – activity» relationship. Ivachtchenko A.V., Golovina E. S.. Kadieva M. G. et al. Bioorg. Med. Chem. Lett. 2012, 22, 4273-4280.
5. Antagonists of serotonin receptor subtype 5-HT6. I. Screening sampling the structurally diverse heterocyclic compounds containing a sulfonyl moiety. Ivachtchenko A.V., Golovina E.S., Kadieva M.G. et al. Khim.-Farm. Zh. (Russian) 2012, 46, (5), 48-58.
6. Antagonists of serotonin receptor subtype 5-HT6. II. The structure – activity relationship of (4-phenylsulfonyl-oxazol-5-yl) amine. Ivachtchenko A.V., Golovina E.S., Kadieva M.G. et al., . Khim.-Farm. Zh. (Russian) 2012, 46(11), 55-62.
7. Antagonists of serotonin receptor subtype 5-HT6. III. Synthesis and structure – activity relationship of amines containing the 3-(arylsulfonyl)-2- (methylthio)pyrazolo[1,5-a]pyrimidine moiety. Ivachtchenko A.V., Golovina E.S., Kadieva M.G. et al. Khim.-Farm. Zh. (Russian) 2012, 46(10), 40-47.
8. Antagonists of serotonin receptor subtype 5-HT6. IV. Ivachtchenko A.V., Golovina E.S., Kadieva M.G. et al. Khim.-Farm. Zh. (Russian) 2012, 46(6), 36-45.
9. Antagonists of serotonin receptor subtype 5-HT6. V. Synthesis, the structure – activity relationship of substituted pyridine 3-(phenylsulfonyl)pyrazolo[1,5-a]- pyrimidine. Ivachtchenko A.V., Golovina E.S., Kadieva M.G. et al. Khim.-Farm. Zh. (Russian) 2012, 46 (7), 55-59.
10. Synthesis and SAR of 3-arylsulfonyl-pyrazolo[1,5-a]pyrimidines as potent serotonin 5-HT6 receptor antagonists. Ivachtchenko A.V., Golovina E.S., Kadieva M.G. et al. Ivachtchenko A.V., Golovina E.S., Kadieva M.G. et al. Bioorg. Med. Chem. 2011, 19, 1482–1491.
11. 2-Substituted 5,6-dimethyl-3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidines: New series of highly potent and specific serotonin 5-HT6 receptor antagonists. Ivachtchenko A.V., Golovina E.S., Kadieva M.G. et al. Eur. J. Med. Chem. 2011, 46 1189-1197.
12. Synthesis and Structure Activity Relationship (SAR) of (5,7-disubstituted 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidin-2-yl)-methylamines as Potent Serotonin 5-HT6 Receptor (5-HT6R) Antagonists. Ivachtchenko A.V., Golovina E.S., Kadieva M.G. et al. J. Med. Chem. 2011, 54, 8161-8173.
13. Synthesis and biological activity of 5-styryl and 5-phenethyl-substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles. Ivachtchenko A.V., Frolov E.B., Mitkin O.D. et al. Bioorg. Med. Chem. Lett. 2010, 20(1), 78–82.
14. Synthesis of cycloalkane-annelated 3-phenylsulfonyl-pyrazolo[1,5-a]pyrimidines and their evaluation as 5-HT6 receptor antagonists. Ivachtchenko A.V.; Dmitriev D.E.; Golovina E.S. et al. Bioorg. Med. Chem. Lett. 2010, 20(7), 2133–2136.
15. 8-Sulfonyl-substituted tetrahydro-1H-pyrido[4,3-b]indoles as 5-HT6 receptor antagonists. Ivachtchenko A.V.; Mitkin O.D.; Tkachenko S.E. et al. Eur. J. Med. Chem., 45(2), 782–789 (2010).
16. Synthesis and biological study of 3-(phenylsulfonyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines as potent and selective serotonin 5-HT6 receptor antagonists. Ivachtchenko A.V.; Golovina E.S.; Kadieva M.G. et al. Bioorg. Med. Chem. 2010, 18, 5282–5290.
17. Solution Phase Parallel Synthesis of Substituted 3-Phenylsulfonyl-[1,2,3]triazolo[1,5-a]quinazolines: Selective Serotonin 5-HT6 Receptor Antagonists. Ivachtchenko A.V.; Golovina E.S.; Kadieva M.G. et al. J. Comb. Chem. 2010, 12, 445–452.
18. (3-Phenylsulfonylcycloalkano[e and d]pyrazolo[1,5-a]pyrimidin-2-yl)amines: Potent and Selective Antagonists of the Serotonin 5-HT6 Receptor. Ivachtchenko A.V.; Dmitriev D.E.; Golovina E.S. et al. J. Med. Chem, 2010, 53, 5186–5196.
19. Synthesis of hydrogenated 2,7-dimethylpyrrolo[3,4-b]indoles – analogs of Dimebon. Ivachtchenko A.V., Frolov E.B., Mitkin O.D. et al. Heterocyclic Comp. 2010, 46(2), 170-178.
20. Synthesis and Biological Evaluation of Novel Bioisosteric Analogues of DimebonTM. Ivaschenko A.V., Frolov E.B., Mitkin O.D. et al. LDDD, 2010, 7(6), 446-451.
21. Synthesis of 5- and 8-substituted 2-methyl-2,3,4,5-tetrahydro-1H-?-carbolines – anatogonists of the serotonin 5-HT6 receptors. Ivaschenko A.V., Frolov E.B., Mitkin O.D. et al. Izv. Vyssh. Ucheb. Zaved., Khim. Khim. Tekhnol. (Russian) 2009, 52(10), 55–60.
22. Synthesis of substituted 1,2,3,4,5,6-hexahydroazepine[4,3-b]indoles. .Ivaschenko A.V., Frolov E.B., Mitkin O.D. et al. Izv. Vyssh. Ucheb. Zaved., Khim. Khim. Tekhnol. (Russian) 2009, 52(10), 66–72.
23. Synthesis of substituted 6-benzyl and 6-(pyridinylmethyl)-1,2,3,4,5,6-hexahydroazepine[4,3-b]indoles. Ivaschenko A.V., Frolov E.B., Mitkin O.D. et al. Izv. Vyssh. Ucheb. Zaved., Khim. Khim. Tekhnol. (Russian) 2009, 52(10), 73–77.
24. The synthesis of substituted 5-sulfonyl-2,3,4,5-tetrahydro-1H-?-carbolines. Ivaschenko A.V., Mitkin O.D., Kysil V.M. et al. Izv. Vyssh. Ucheb. Zaved., Khim. Khim. Tekhnol. (Russian) 2009, 52(10), 78–83.
25. The synthesis of substituted 2-sulfonyl-2,3,4,5-tetrahydro-1H-?-carbolines. Ivaschenko A.V., Mitkin O.D., Kysil V.M. et al. Izv. Vyssh. Ucheb. Zaved., Khim. Khim. Tekhnol. (Russian) 2009, 52(10), 83–87.
26. Synthesis of 6-substituted 1,2,3,4,5,6-hexahydroazepine4,3-b]indoles. Ivaschenko A.V., Mitkin O.D., Frolov E.B. et al. Izv. Vyssh. Ucheb. Zaved., Khim. Khim. Tekhnol. (Russian) 2009, 52(10), 88–93 (2009).
27. Synthesis and Biological Evaluation of Novel 5,8-Disubstituted-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles as 5-HT6 and H1 Receptors Antagonists. Ivachtchenko A.V.; Frolov, E. B.; Mitkin, O. D. et al. Arch. Pharm. 2009, 342(12), 740–747.
28. Synthesis and biological evaluation of novel ?-carboline analogues of Dimebon as potent 5-HT6 receptor antagonists. Ivachtchenko, A. V.; Frolov, E. B.; Mitkin, O. D. et al. Bioorg. Med. Chem. Lett. 2009, 19(12), 3183–3187