1. PATENTS OF A SELECTIVE 5-HT6 RECEPTOR ANTAGONIST PLATFORM

3-Sulfonyl-pyrazolo[1,5-a]pyrimidines – antagonists of serotonin 5-HT6 receptors, methods for the production and the use thereof. Ivashchenko A.A., Ivachtchenko A.V., Savchuk N.F. Patent JP 5690594 (2015)

Substituted 2-amino-3-sulfonyl-pyrazolo[1,5-a]pyrimidines – antagonists of serotonin 5-ht6 receptors, methods for the production and the use thereof. Ivashchenko A.A., Ivashchenko A.V., Savchuk N.F. Patent ?? 2248817 (2015).

Substituted methyl amines serotonin 5-HT6 receptor antagonists, method for the production and use thereof. Ivachtchenko A.V., Mitkin O.D., Kadieva M.G.
Patent US 8,829,002 (2014).

2-Alkylamino-3-arylsulfonyl-cycloalkane[e or d]pyrazolo[1,5-a]pyrimidines – antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Patent ?? 2248816 (2014).

Tetrahydro-pyrazolo[1,5-a]pyrido-pyrimidines as antagonists of serotonin 5-ht6 receptors, methods for the production and use thereof. Kysil V.M., Savchuk N.F., Ivashchenko A.V. et al. Patent EP 2305678 (2014).

2-Amino-3-sulfonyl-tetrahydro-pyrazolo[1,5-a]pyrido-pyrimidines – serotonin 5-HT6 receptor antagonists, methods for their preparation and use. Ivashchenko A.A., Kysil V.N., Savchuk N.F., Patent UA 102844 (2013).

2-Amino-3-sulfonyl-tetrahydro-pyrazolo[1,5-a]pyrido-pyrimidines – serotonin 5-HT6 receptor antagonists, methods for their preparation and use. Ivashchenko A.A., Kysil V.N., Savchuk N.F., Patent UA 102845 (2013).

2-Amino-3-sulfonyl-tetrahydro-pyrazolo[1,5-a]pyrido-pyrimidines – serotonin 5-HT6 receptor antagonists, methods for their preparation and use. Ivashchenko A.A., Kysil V.N., Savchuk N.F., Patent ?? 017117 (2013).

Substituted 3-arylsulfonyl-pyrazolo[1,5-a]pyrimidines, antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. at al. Patent ?? 017630 (2013).

2-Alkylamino-3-arylsulfonyl-cycloalkane[e or d]pyrazolo[1,5-a]pyrimidines – antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Patent ?? 017805 (2013).

3-Sulfonylpirazolo[1,5-a]pyrimidines – antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Patent ?? 017817 (2013).

Substituted cycloalkane[e or d]pyrazolo[1,5-a]pyrimidines – antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Patent ?? 017818 (2013).

Substituted methyl amines, serotonin 5-HT6 receptor antagonists, method for the production and use thereof. Ivachtchenko A.V., Mitkin O.D., Kadieva M.G. WO/2012/087182 (2012).

Substituted methyl-amines, antagonists of serotonin 5-HT6 receptor, methods of preparation and use. Ivachtchenko A.V., Mitkin O.D., Kadieva M.G. Patent RU 2443697 (2012).

Substituted 2-amino-3-sulfonyl-pyrazolo[1,5-a]pyrimidines – antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Patent UA 100137 (2012).

Substituted cycloalkano[e or d]pyrazolo[1,5-a]pyrimidines – antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Patent UA 100138 (2012).

Substituted 3-arylsulfonyl-pyrazolo[1,5-a]pyrimidine-2,6-diamine, antagonists of serotonin 5-HT6 receptor, methods of preparation and use. Ivachtchenko A.V., Savchuk N.F., Ivashchenko A.A. Patent RU 2421456 (2011).

2-Amino-3-sulphonyl-tetrahydro-pyrazolo[1,5-a]pyrido-pyrimidine antagonists of serotonin 5-ht6 receptors, methods for the production and use thereof. Kysil V.M., Savchuk N.F., Ivashchenko A.V. Pat. Appl. EP 2287163 A1 (2011).

Substituted 3-arylsulfonyl-pyrazolo[1,5-a]pyrimidines, serotonin 5-ht6 receptor antagonists and methods for the production and use thereof. Ivashchenko A.V., Savchuk N.F., Lavrovsky Y. et al. Pat. Appl. EP 2351756 A1 (2011).

Substituted 3-arylsulfonyl-pyrazolo[1,5-a]pyrimidines, serotonin 5-ht6 receptor antagonists and methods for the production and use thereof. Ivashchenko A.A., Ivashchenko A.V., Savchuk N.F. et al. WO/2010/041983 (2010).

3-Sulfonyl-pyrazolo[1,5-a] pyrimidines / antagonists of serotonin 5-ht6 receptors, methods for the production and the use thereof. Ivashchenko A.A., Ivachtchenko A.V., Savchuk N.F. Pat. Appl. US 20100331347 A1 (2010).

3-Sulfonyl-pyrazolo[1,5-a]pyrimidines / antagonists of serotonin 5-ht6 receptors, methods for the production and the use thereof. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Pat. Apl. EP 2248815 A2 (2010).

Substituted 2-amino-3-sulfonyl-pyrazolo[1,5-a] pyrimidines – antagonists of serotonin 5-ht6 receptors, methods for the production and the use thereof. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Pat. Apl. EP 2248817 A2 (2010).

Substituted 3-sulfonyl-tetrahydro-pyrazolo[1,5-a]pyrido-pyrimidines – antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Patent RU 2384581 (2010).

2-Alkylamino-3-arylsulfonyl-pyrazolo[1,5a]pyrimidines, antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Patent RU 2393157 (2010).

Substituted 3-arylsulfonyl-pyrazolo[1,5a]pyrimidines, antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Patent RU 2393158 (2010).

Substituted 2-alkylsulfanyl-3-sulfonyl-pyrazolo[1,5-a]pyrimidines, antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Patent RU 2393159 (2010).

Substituted 2-alkylamino-3-sulfonyl-pyrazolo[1,5-a]pyrimidines, antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Patent RU 2399621 (2010).

Substituted cycloalkane[e or d]pyrazolo[1,5-a]pyrimidines – antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Savchuk N.F., Ivashchenko A.A. Patent RU 23674249 (2009).

Substituted 4-(arylsulfonyl)pyrazoles and 3 (arylsulfonyl)pyrazolo[1,5-a]pyrimidines – antagonists of serotonin 5-HT6 receptors, the active components. A pharmaceutical composition, drug and methods for their preparation. Ivachtchenko A.V., Savchuk N.F., Ivashchenko A.A. Patent RU 2369600 (2009).

3-Sulfonyl-pyrazolo[1,5-a]pyrimidines / antagonists of serotonin 5-ht6 receptors, methods for the production and the use thereof. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. WO 2009/093206 (2009).

Substituted 2-amino-3-sulfonyl-pyrazolo[1,5-a] pyrimidines – antagonists of serotonin 5-ht6 receptors, methods for the production and the use thereof. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. WO 2009/093208 (2009).

2-Alkylamino-3-arylsulfonyl-pyrazolo[1,5a]pyrimidines, antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. Ivashchenko, A. A.; Ivashchenko, A. V.; Savchuk, N. F. WO 2009/093209 (2009).

Substituted cycloalkane[e or d]pyrazolo[1,5-a]pyrimidines – antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivashchenko, A. A.; Ivashchenko, A. V.; Savchuk, N. F. WO 2009/093210 (2009).

Substituted 3-sulfonyl-tetrahydro-pyrazolo[1,5-a]pyrido-pyrimidines – antagonists of serotonin 5-HT6 receptors, processes for their preparation and use. Ivachtchenko A.V., Ivashchenko A.A., Savchuk N.F. WO 2009/093934 (2009).

2-Amino-3-sulfonyl-6,7,8,9-tetrahydro-pyrazolo[1,5-a]pyrido[4,3-e]pyrimidines as seroto-nin 5-HT6 receptor antagonists and process for their production. Ivashchenko, A.A.; Kysil, V.M.; Savchuk, N.F.; Ivashchenko, A.V. WO 2009/136813 (2009).

Tetrahydro-pyrazolo[1,5-a]pyrido-pyrimidines as antagonists of serotonin 5-ht6 receptors, methods for the production and use thereof. Ivashchenko, A A; Kysil, V. M.; Savchuk, N. F.; Ivashchenko, A. V. WO 2009136814 (2009).

Substituted 2,3,4,5-tetrahydro-1H- pyrido[4,3-b]indoles, their preparation and use. Ivachtchenko A.V., Tkachenko S.E., Frolov E.B. et al. Patent RU 2334747 (2008).

Substituted azepino[4,3-b]indoles, pharmaceutical compositions, processes for their preparation and use. Ivashchenko, A.A.; Frolov, E.B.; Tkachenko, S.E. et al. WO 2008024029 (2008).

2. PATENTS OF A MULTI-TARGET PLATFORM

Substituted 8-sulfonyl-2,3,4,5-tetrahydro-1H-gamma-carbolines, ligands and pharmaceutical composition; vethod for the production and use of same. Ivashchenko A.A., Ivashchenko A.V., et al. Patent EA 018944 (2013).

Ligand with a broad spectrum of pharmacological activity, a pharmaceutical composition, a medicinal agent and a method of treatment. Ivashchenko A.A., Ivashchenko A.V., Savchuk N.F. Patent ?? 018788 (2013).

Substituted hydrogenated thieno-pyrrolo[3,2-c]pyridine, ligands, a pharmaceutical composition and a method for the using the above. Ivachtchenko A.V., Mitkin O.D. WO/2012/091628 (2012).

Substituted azepino[4,3-b]indoles, pharmacological composition and a method for the production and use thereof. Ivachtchenko A.V.: Ivashchenko A.A., Frolov E.B. et al. Pat. Appl. US 20120040965 A1 (2012).

Substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles, their preparation and use. Ivachtchenko A.V.: Ivashchenko A.A., Frolov E.B. et al. Patent ?? 016234 (2012).

Substituted hydrogenated thieno-pyrrolo[3,2-c]pyridine, ligands, a pharmaceutical composition and a method for the using the above. Ivachtchenko A.V., Mitkin O.D. Patent RU 2451686 (2012).

Substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles, their preparation and use. Ivachtchenko A.V., Tkachenko S.E., Frolov E.B. Patent UA 98324 (2012).

Ligands of 5-ht6 receptors, a pharmaceutical composition, method for the production and use thereof. Ivachtchenko A.V., Ivashchenko A.A., Okun I.M. et al. Pat. Appl. US 20110046368 A1 (2011).

Ligands of alpha-adrenoceptors, dopamine, histamine, imidazoline and serotonin receptors and their use. Ivashchenko A.A., Ivachtchenko A.V., Lavrovsky Y.V. et al. Pat. Appl. US 20110039825 A1 (2011).

Ligand with a broad spectrum of pharmacological activity, a pharmaceutical composition, a medicinal agent and a method of treatment. Ivashchenko A.A., Ivashchenko A.V., Savchuk N.F. WO/2010/024717 (2010).

Substituted 8-sulfonyl-2,3,4,5-tetrahydro-1H-gamma-carbolines, ligands and pharmaceutical composition; vethod for the production and use of same. Ivashchenko A.A., Ivashchenko A.V., Kysil V.M. et al. WO/2010/134846 (2010).

Substituted 2,3,4,5-Tetrahyrdo-1H-Pyrido[4,3-b]indoles, Methods for the Production and Use Thereof. Frolov E.B., Ivachtchenko A.V., Lavrovsky Y. et al. Pat. Appl. US 20100120792 A1 (2010).

Ligands of 5-ht6 receptors, a pharmaceutical composition, method for the production and use thereof. Ivashchenko A.V., Ivashchenko A.A., Okun I.M. et al. Pat. Appl. EP 2184064 A2 (2010).

Substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles, methods for the production and use thereof. Frolov E.B., Ivachtchenko A.V., Ivachtchenko A.A. et al. Pat. Apl. EP 2145887 A2 (2010).

Ligands of alpha-adrenoceptors and of dopamine, histamine, imidazoline and serotonin receptors and the use thereof. Ivachtchenko A.V., Ivashchenko A.A., Lavrovsky Y.V. et al. Pat. Appl. EP 2236511 A2 (2010).

Substituted 3-sulfonyl[1,2,3]triazolo[1,5-a]pyrimidine – 5-HT6 antagonists serotononinovyh receptors, processes for their preparation and use. Ivachtchenko A.V., Savchuk N.F., Ivashchenko A.A. Patent RU 2378278 (2010).

2-Amino-3-sulfonyl-tetrahydro-pyrazolo[1,5-a]pyrido-pyrimidines – serotonin 5-HT6 receptor antagonists, methods for their preparation and use. Ivashchenko A.A., Kysil V.N., Savchuk N.F., Patent RU 2391343 (2010).

Ligands ?-adrenoceptor, dopamine, histamine, imidazoline and serotonin receptors and their use. Ivachtchenko A.V., Ivashchenko A.A., Lavrovsky Y.V. et al. Patent RU 2407744 (2010).

Substituted 8-sulfonyl-2,3,4,5-tetrahydro-1H-gamma-carbolines, ligands, pharmaceutical compositions, processes for their preparation and use. Ivachtchenko A.V., Kysil V.M., Mitkin O.D. et al. Patent RU 2404180 (2010).

Ligand with a broad spectrum of receptor activity simultaneously, a pharmaceutical composition and method of producing the drug. Ivashchenko A.A., Ivachtchenko A.V., Savchuk N.F. Paent RU 2374245 (2009).

Ligands ?-adrenoceptor, dopamine, histamine, imidazoline and serotonin receptors and their use. Ivachtchenko A.V., Ivashchenko A.A., Lavrovsky Y.V. et al. WO 2009/082268 (2009).

Ligands of 5-ht6 receptors, a pharmaceutical composition, method for the production and use thereof. Ivashchenko, A.A.; Ivashchenko, A.V.; Tkachenko S.E. et al. WO 2008/060190 (2008).